RNU6-87P

Across TCGA pan-cancer cohorts, RNU6-87P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-87P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-87P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-87P expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

UVM, KIRC, and READ are the cancer types where RNU6-87P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.451	0.809	<.001	81	view →
KIRC	OS	Tertile	All	0.745	0.830	<.001	65	view →
READ	DFS	Tertile	All	0.351	0.781	<.001	45	view →
BRCA	OS	Tertile	III,IV	0.969	0.874	.003	42	view →
CESC	DFS	Tertile	IV	0.215	0.539	.042	18	view →
LIHC	DFS	Quartile	II,III,IV	0.264	0.461	.002	18	view →
THCA	DFS	Median	IV	0.639	0.898	.014	12	view →
MESO	DFS	Median	III,IV	0.554	0.324	.021	12	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	9	view →
COAD	DFS	Tertile	II,III,IV	0.885	0.745	.039	6	view →
CHOL	OS	Median	II,III,IV	0.867	0.414	.044	3	view →
LGG	DFS	Quartile	All	0.666	0.760	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-87P–UVM (DFS)

Open the UVM breakdown →