Across TCGA pan-cancer cohorts, RNU6-878P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-878P’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RNU6-878P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-878P is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

PAAD, LUSC, and LUAD are the cancer types where RNU6-878P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-878P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Female	All	+1.085	.001	4	view →
LUSC	All	All	−0.147	.024	2	view →
LUAD	All	II,III,IV	−0.251	.016	1	view →
COAD	All	II,III,IV	−0.183	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-878P RNA expression & survival · all RNU6-878P data types