Across TCGA pan-cancer cohorts, RNU6-877P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-877P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU6-877P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-877P is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where RNU6-877P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-877P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.166	.022	3	view →
COAD	Female	II,III,IV	−0.136	.038	3	view →
KIRC	Male	All	+0.078	.011	3	view →
LIHC	Female	All	+0.150	.021	1	view →
THCA	All	II,III,IV	−0.123	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-877P RNA expression & survival · all RNU6-877P data types