RNU6-869P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-869P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-869P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-869P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-869P expression acts as an unfavorable survival marker, although some lineages such as LGG and SKCM show a favorable association.

STAD, THCA, and UVM are the cancer types where RNU6-869P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileAll0.3080.571<.00172view →
THCADFSTertileAll0.5250.839.00254view →
UVMDFSTertileAll0.0710.746<.00136view →
LGGOSTertileAll0.9650.861<.00131view →
SKCMOSTertileAll0.5290.310.00127view →
UCECOSTertileAll0.8950.928.01324view →
UCSDFSTertileAll0.1330.455.02818view →
COADDFSTertileIV0.0280.496<.00118view →
KIRPDFSTertileAll0.6610.878.00418view →
PAADDFSTertileII,III,IV0.6470.397.0353view →
ACCOSTertileII,III,IV0.5480.878.0453view →
SARCOSTertileAll0.7400.837.0233view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration