RNU6-856P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-856P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-856P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-856P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-856P expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

KIRC, UCEC, and LGG are the cancer types where RNU6-856P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianIII,IV0.5410.740.00368view →
UCECOSTertileAll0.5120.770.00134view →
LGGOSMedianAll0.3150.553.00118view →
LIHCDFSQuartileAll0.4110.592.00113view →
LUADOSQuartileAll0.3530.199.00411view →
SKCMDFSTertileII,III,IV0.4190.248.01410view →
KICHDFSMedianAll0.7990.973.0139view →
READDFSQuartileIV0.2170.650.0059view →
ESCADFSMedianAll0.4500.608.0114view →
DLBCDFSQuartileAll0.5260.860.0214view →
TGCTDFSTertileII,III,IV0.6341.000.0294view →
SARCOSMedianAll0.5050.686.0364view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-856P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-856P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration