RNU6-850P

Across TCGA pan-cancer cohorts, RNU6-850P RNA is linked to patient survival in 30 of 34 cancer types, making it the most broadly survival-associated RNU6-850P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-850P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-850P expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

KICH, LGG, and KIRC are the cancer types where RNU6-850P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	II,III,IV	0.528	0.927	<.001	67	view →
LGG	DFS	Median	All	0.290	0.461	<.001	52	view →
KIRC	DFS	Tertile	All	0.498	0.733	<.001	50	view →
COAD	DFS	Median	III,IV	0.233	0.710	<.001	45	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
BRCA	OS	Tertile	All	0.976	0.938	.001	35	view →
READ	OS	Tertile	II,III,IV	0.861	0.257	.001	34	view →
BLCA	DFS	Median	All	0.438	0.259	.001	28	view →
STAD	OS	Tertile	III,IV	0.525	0.786	.001	26	view →
SKCM	DFS	Tertile	II,III,IV	0.449	0.730	<.001	26	view →
ACC	OS	Quartile	All	0.248	0.902	<.001	26	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 30 lineages.

RNU6-850P–KICH (DFS)

Open the KICH breakdown →