RNU6-844P

Across TCGA pan-cancer cohorts, RNU6-844P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-844P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-844P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-844P is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and THCA are the cancer types where RNU6-844P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-844P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.846	<.001	12	view →
KIRP	All	All	−0.945	<.001	9	view →
THCA	Female	All	−0.703	<.001	8	view →
HNSC	All	II,III,IV	−0.167	.013	3	view →
LUAD	Female	II,III,IV	−0.449	.039	1	view →
STAD	Male	II,III,IV	+0.295	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-844P–KIRC

Open the KIRC breakdown →