RNU6-840P

Across TCGA pan-cancer cohorts, RNU6-840P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-840P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-840P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-840P expression acts as an unfavorable survival marker, although some lineages such as GBM and PRAD show a favorable association.

KIRC, ACC, and KIRP are the cancer types where RNU6-840P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.330	0.662	.001	81	view →
ACC	DFS	Tertile	All	0.077	0.673	<.001	60	view →
KIRP	OS	Tertile	III,IV	0.095	0.521	.001	57	view →
CESC	OS	Tertile	III,IV	0.531	0.806	.006	54	view →
COAD	OS	Tertile	All	0.770	0.887	.011	45	view →
STAD	OS	Quartile	III,IV	0.487	0.740	.004	43	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	33	view →
HNSC	OS	Tertile	IV	0.275	0.661	.007	30	view →
UCEC	OS	Tertile	All	0.866	0.929	.008	30	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
GBM	OS	Tertile	All	0.412	0.166	.011	15	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-840P–KIRC (DFS)

Open the KIRC breakdown →