RNU6-840P

Across TCGA pan-cancer cohorts, RNU6-840P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-840P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNU6-840P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-840P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, LUSC, and BRCA are the cancer types where RNU6-840P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-840P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.328	.003	4	view →
LUSC	Female	III,IV	+1.070	.002	2	view →
BRCA	All	IV	+0.900	<.001	2	view →
LUAD	Female	All	+0.201	.043	1	view →
THCA	All	All	−0.115	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNU6-840P–COAD

Open the COAD breakdown →