RNU6-82P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-82P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-82P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-82P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-82P expression acts as an unfavorable survival marker, although some lineages such as STAD and LAML show a favorable association.

CHOL, CESC, and STAD are the cancer types where RNU6-82P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLDFSTertileAll0.0300.500<.001135view →
CESCOSTertileAll0.6240.816.00566view →
STADOSTertileIII,IV0.7340.506<.00156view →
HNSCOSTertileII,III,IV0.2530.613.00545view →
MESODFSTertileIII,IV0.1570.425.01036view →
LAMLDFSQuartileAll0.6130.218<.00136view →
BRCAOSTertileIII,IV0.7850.469.01330view →
ACCOSTertileIV0.1450.715<.00127view →
UCSOSTertileAll0.1850.686.03418view →
UCECOSTertileIV0.3080.748.00918view →
ESCAOSQuartileAll0.3400.569.01316view →
SARCOSTertileAll0.2020.535.00512view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration