Q-omics provides the consensus-scored RNU6-82P profile across patient tissues and cancer cell-line models. RNU6-82P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in CHOL. Among the 18 cancer types available for tumor–normal comparison, RNU6-82P is differentially expressed in 4, with the highest sampling consensus in STAD. Additionally, RNU6-82P RNA expression shows 7,267 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight CHOL, STAD, and LAML as cancer lineages where RNU6-82P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-82P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-82P survival associations across molecular data types. RNU6-82P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-82P RNA expression–survival associations across cancer types. High RNU6-82P expression shows unfavorable associations in CHOL, CESC, HNSC and MESO, but favorable associations in STAD and LAML. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CHOL as the clearest survival context for RNU6-82P RNA expression.
This table summarizes RNU6-82P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-82P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-82P shows lower tumor expression in HNSC and higher tumor expression in STAD, LUAD and KIRC. The STAD box plot shows higher RNU6-82P RNA expression in tumor versus normal tissue (log2 FC = +1.002, t-test p = .002).
This table shows molecular features associated with RNU6-82P in patient tissues and cancer cell lines. In patient samples, RNU6-82P shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
