RNU6-721P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-721P mutation is significantly associated with the RNA expression of many other genes, with 267 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU6-721P-associated genes across cancer lineages are RN7SL62P, DNAJC19P3, and FAM27B. Each is linked with RNU6-721P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-721P-to-partner and partner-to-RNU6-721P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-721P→partner) and Y-score (partner→RNU6-721P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL62P →+0.132+4.812<.001.00632
CESCDNAJC19P3 →+0.329+4.503<.001.00532
CESCFAM27B →+0.124+4.812<.001.00632
LUSCRNA5SP424 →+0.241+5.309<.001.00332
CESCNOS2P1 →+0.013+4.669<.001.00731
CESCCYP4F10P →+0.124+4.601<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 267 associations by consensus.

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