RNU6-720P

Across TCGA pan-cancer cohorts, RNU6-720P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-720P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU6-720P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-720P is over-expressed in tumor, although a few such as READ and THCA show the opposite, repressed pattern.

HNSC, READ, and THCA are the cancer types where RNU6-720P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-720P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.471	<.001	9	view →
READ	Male	All	−0.726	.004	5	view →
THCA	Male	All	−0.587	.006	3	view →
LUSC	All	All	+0.501	<.001	3	view →
KICH	Female	II,III,IV	−0.514	.040	1	view →
KIRC	All	III,IV	+0.301	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-720P–HNSC

Open the HNSC breakdown →