RNU6-6P

Across TCGA patient cohorts, RNU6-6P RNA expression is significantly associated with the go_rna of many other GO terms, with 4,587 significant associations in total. LGG shows the largest number of these associations.

The most reproducible RNU6-6P-associated GO terms across cancer lineages are Regulation of centrosome cycle, Mitotic sister chromatid cohesion, and Mitotic metaphase chromosome alignment. Each is linked with RNU6-6P in more than 10 cancer types. Because this analysis shows association rather than direction, both RNU6-6P-to-partner and partner-to-RNU6-6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome cycle grouped by RNU6-6P-low versus RNU6-6P-high in LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-6P→partner) and Y-score (partner→RNU6-6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Regulation of centrosome cycle →	+0.028	+0.181	<.001	<.001	3	10
THYM	Mitotic sister chromatid cohesion →	+0.050	+0.473	<.001	<.001	3	10
THYM	Mitotic metaphase chromosome alignment →	+0.047	+0.326	<.001	<.001	3	10
THYM	Recombinational repair →	+0.026	+0.479	<.001	<.001	3	10
THYM	Cell cycle checkpoint signaling →	+0.035	+0.445	<.001	<.001	3	10
THYM	DNA conformation change →	+0.033	+0.461	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,587 associations by consensus.

Regulation of centrosome cycle by RNU6-6P expression — LUAD

Explore this box plot interactively →