RNU6-677P

Across TCGA pan-cancer cohorts, RNU6-677P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-677P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-677P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-677P expression acts as an unfavorable survival marker, although some lineages such as BLCA and LAML show a favorable association.

KICH, BLCA, and LAML are the cancer types where RNU6-677P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.451	0.960	<.001	93	view →
BLCA	DFS	Tertile	All	0.510	0.273	.002	90	view →
LAML	DFS	Tertile	All	0.546	0.321	.002	40	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	36	view →
KIRC	DFS	Tertile	IV	0.396	0.693	.011	24	view →
OV	DFS	Tertile	IV	0.250	0.480	.024	18	view →
THCA	OS	Tertile	IV	0.581	0.877	.035	15	view →
LUSC	OS	Tertile	All	0.930	0.777	.036	15	view →
PAAD	DFS	Tertile	All	0.193	0.380	.020	9	view →
COAD	OS	Tertile	IV	0.153	0.678	.034	9	view →
LIHC	DFS	Tertile	III,IV	0.824	0.290	.036	9	view →
LGG	DFS	Tertile	All	0.953	0.711	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-677P–KICH (OS)

Open the KICH breakdown →