RNU6-677P

Across TCGA pan-cancer cohorts, RNU6-677P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-677P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU6-677P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-677P is over-expressed in tumor.

HNSC and BRCA are the cancer types where RNU6-677P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-677P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.166	.006	5	view →
BRCA	All	III,IV	+0.310	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNU6-677P–HNSC

Open the HNSC breakdown →