RNU6-667P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-667P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-667P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-667P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-667P expression acts as an unfavorable survival marker, although some lineages such as LUAD and STAD show a favorable association.

TGCT, COAD, and ESCA are the cancer types where RNU6-667P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileII,III,IV0.5010.996<.00160view →
COADOSTertileIV0.0390.660<.00145view →
ESCAOSTertileIV0.0950.512.00836view →
MESODFSTertileIV0.0590.361.00236view →
KIRCOSQuartileII,III,IV0.6910.805.01022view →
ACCDFSTertileAll0.1240.644.00621view →
LUADDFSTertileAll0.9130.305.01412view →
STADDFSTertileIV0.5200.250.0339view →
BLCADFSTertileAll1.0000.336.0389view →
UVMDFSTertileIII,IV0.0790.635.0219view →
SKCMDFSTertileIV0.0400.432.0389view →
KIRPOSTertileAll0.4700.728.0216view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-667P–TGCT (OS)

Kaplan–Meier survival curve for RNU6-667P RNA-high vs -low samples in TGCT.

Open the TGCT breakdown →

Exploration