RNU6-667P

associated omics data
RNA, U6 small nuclear 667, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-667P profile across patient tissues and cancer cell-line models. RNU6-667P expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in TGCT. Among the 18 cancer types available for tumor–normal comparison, RNU6-667P is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, RNU6-667P RNA expression shows 10,299 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight TGCT, BRCA, and THYM as cancer lineages where RNU6-667P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-667P survival associations across molecular data types. RNU6-667P RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-667P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier13TGCT (60)view →
This table ranks reproducible RNU6-667P RNA expression–survival associations across cancer types. High RNU6-667P expression shows unfavorable associations in TGCT, COAD, MESO, ESCA, KIRC and ACC. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for RNU6-667P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileII,III,IV0.5010.996<.00160view →
COADOSTertileIV0.0390.660<.00145view →
MESODFSTertileIV0.0590.361.00236view →
ESCAOSTertileIV0.0950.512.00836view →
KIRCOSQuartileII,III,IV0.6910.805.01022view →
ACCDFSTertileAll0.1240.644.00621view →
Pink = unfavorable, green = favorable. all 13 lineages →

RNU6-667P-TGCT (OS)

Kaplan–Meier survival curve for RNU6-667P RNA expression in TGCT: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-667P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
RNU6-667P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot1BRCA (2)view →
This table ranks reproducible tumor–normal expression differences for RNU6-667P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-667P shows lower tumor expression in BRCA. The BRCA box plot shows higher RNU6-667P RNA expression in normal versus tumor tissue (log2 FC = −0.212, t-test p = .019).
LineageGenderStageFold-changepSampling consensus
BRCAAllIII,IV−0.212.0192view →
Green = repressed in tumor. all 1 lineages →

RNU6-667P-BRCA

Tumor-vs-normal expression box plot for RNU6-667P in BRCA.

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Cross-omics associations

This table shows molecular features associated with RNU6-667P in patient tissues and cancer cell lines. In patient samples, RNU6-667P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA10,299THYM (2961)view →
Protein (mass-spec)6,647GBM (2732)view →