RNU6-644P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-644P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-644P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-644P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-644P expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

KIRC, OV, and LIHC are the cancer types where RNU6-644P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIV0.2670.551<.00158view →
OVOSTertileAll0.9030.826.01948view →
LIHCDFSTertileAll0.2700.563.00133view →
PCPGDFSTertileAll0.5320.903.00230view →
CESCOSTertileIV0.0950.592.00418view →
UCSDFSTertileIV0.9960.570.03918view →
THCAOSTertileAll0.9820.995.01315view →
SKCMOSTertileIV0.1790.727<.00115view →
ESCADFSTertileIV0.2160.542.02112view →
LGGDFSTertileAll0.8550.760.00412view →
BRCAOSTertileII,III,IV0.8640.921.01512view →
LAMLDFSTertileAll0.5100.321.03610view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration