Across TCGA pan-cancer cohorts, RNU6-644P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-644P’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNU6-644P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-644P is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.

BLCA, LUSC, and STAD are the cancer types where RNU6-644P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-644P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−0.218	.015	4	view →
LUSC	All	All	−0.162	.003	4	view →
STAD	Male	All	+0.318	.006	3	view →
KIRP	Male	All	−0.142	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-644P RNA expression & survival · all RNU6-644P data types