RNU6-642P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-642P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-642P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-642P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-642P expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

MESO, LIHC, and OV are the cancer types where RNU6-642P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIV0.0360.602<.001144view →
LIHCOSTertileII,III,IV0.0720.720<.00172view →
OVDFSTertileAll0.2230.146.02636view →
CESCDFSTertileIII,IV0.0940.443.01330view →
UCSOSTertileAll1.0000.316.04024view →
UCECDFSTertileIV1.0000.387.04824view →
BLCADFSTertileAll0.3600.608.02818view →
KIRCDFSTertileAll0.2960.642.01912view →
PRADOSTertileAll0.9330.996.00212view →
SKCMOSTertileII,III,IV0.9330.832.0209view →
COADDFSTertileII,III,IV0.1840.571.0289view →
DLBCOSTertileII,III,IV0.5860.949.0149view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration