RNU6-63P

Across TCGA pan-cancer cohorts, RNU6-63P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-63P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-63P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-63P expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

MESO, SKCM, and KIRC are the cancer types where RNU6-63P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.064	0.576	<.001	180	view →
SKCM	DFS	Tertile	II,III,IV	0.700	0.239	.002	57	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	54	view →
LIHC	OS	Tertile	III,IV	0.113	0.635	<.001	51	view →
ESCA	DFS	Tertile	All	0.324	0.542	.006	48	view →
LUAD	OS	Tertile	III,IV	0.237	0.687	.001	39	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
STAD	DFS	Quartile	All	0.559	0.760	.010	30	view →
HNSC	OS	Tertile	II,III,IV	0.645	0.750	.019	27	view →
LGG	DFS	Tertile	All	0.282	0.733	.008	18	view →
BLCA	OS	Tertile	All	0.872	0.334	.041	6	view →
CESC	DFS	Tertile	II,III,IV	0.244	0.557	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-63P–MESO (OS)

Open the MESO breakdown →