RNU6-628P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-628P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-628P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNU6-628P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-628P expression acts as an unfavorable survival marker, although some lineages such as LAML and STAD show a favorable association.

KIRP, SKCM, and ACC are the cancer types where RNU6-628P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPDFSTertileIV0.0880.502<.00139view →
SKCMDFSTertileIV0.0380.472<.00138view →
ACCOSTertileIII,IV0.3610.779<.00136view →
LAMLDFSMedianAll0.4870.283.00728view →
LUSCOSTertileII,III,IV0.5490.772.00121view →
KIRCDFSQuartileIII,IV0.3110.524.01919view →
LUADDFSTertileIV0.2190.633.04118view →
BRCADFSTertileIII,IV0.7120.825.02614view →
UVMDFSTertileIII,IV0.1290.673.0179view →
OVOSTertileAll0.7800.853.0406view →
STADOSTertileAll0.7760.652.0114view →
DLBCDFSQuartileII,III,IV0.9710.616.0273view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration