Across TCGA patient cohorts, RNU6-59P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,998 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-59P-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Regulation of RNA splicing, and Regulation of Ras protein signal transduction. Each is linked with RNU6-59P in more than 14 cancer types. Because this analysis shows association rather than direction, both RNU6-59P-to-partner and partner-to-RNU6-59P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-59P→partner) and Y-score (partner→RNU6-59P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of post-translational protein modification →	+0.067	+0.564	.001	<.001	3	15
LUSC	Regulation of RNA splicing →	+0.062	+0.037	<.001	.002	3	15
UCEC	Regulation of Ras protein signal transduction →	+0.065	+0.165	<.001	<.001	3	15
ESCA	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.067	+0.475	<.001	<.001	3	15
LUSC	Protein polymerization →	+0.052	+0.045	<.001	.002	3	14
ESCA	Positive regulation of proteasomal protein catabolic process →	+0.065	+0.474	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,998 associations by consensus.

Exploration

RNU6-59P survival (RNA) · tumor vs normal (RNA) · all RNU6-59P data types