RNU6-579P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-579P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-579P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-579P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-579P expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.

LIHC, PAAD, and CHOL are the cancer types where RNU6-579P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.1640.786<.00154view →
PAADDFSTertileAll0.1280.472<.00145view →
CHOLDFSTertileAll0.0450.486.00945view →
READOSTertileAll0.1830.828<.00136view →
UCECOSTertileAll0.7310.879.01224view →
ESCADFSQuartileIV0.8260.309.04012view →
LGGOSTertileAll0.7960.936<.00112view →
KICHDFSTertileAll0.6540.935.0079view →
ACCDFSTertileAll0.1950.748.0039view →
SARCDFSTertileAll0.1620.602.0019view →
OVDFSTertileIV0.8300.425.0316view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-579P–LIHC (OS)

Kaplan–Meier survival curve for RNU6-579P RNA-high vs -low samples in LIHC.

Open the LIHC breakdown →

Exploration