RNU6-579P

Across TCGA pan-cancer cohorts, RNU6-579P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-579P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-579P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-579P is over-expressed in tumor, although a few such as LUSC and KIRC show the opposite, repressed pattern.

KICH, LUSC, and KIRC are the cancer types where RNU6-579P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-579P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	+0.502	.019	3	view →
LUSC	All	All	−0.199	<.001	2	view →
KIRC	All	II,III,IV	−0.098	.019	2	view →
LUAD	All	III,IV	−0.228	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-579P–KICH

Open the KICH breakdown →