RNU6-542P

Across TCGA patient cohorts, RNU6-542P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,304 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-542P-associated GO terms across cancer lineages are Negative regulation of epidermal growth factor-activated receptor activity, Metencephalon development, and Negative regulation of gene expression, epigenetic. Each is linked with RNU6-542P in more than 12 cancer types. Because this analysis shows association rather than direction, both RNU6-542P-to-partner and partner-to-RNU6-542P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of epidermal growth factor-activated receptor activity grouped by RNU6-542P-low versus RNU6-542P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-542P→partner) and Y-score (partner→RNU6-542P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of epidermal growth factor-activated receptor activity →	+0.073	+0.256	<.001	<.001	3	12
STAD	Metencephalon development →	+0.062	+0.265	<.001	<.001	3	11
STAD	Negative regulation of gene expression, epigenetic →	+0.085	+0.253	<.001	<.001	3	11
STAD	Pallium development →	+0.060	+0.227	<.001	<.001	3	11
STAD	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.091	+0.259	<.001	<.001	3	11
STAD	mRNA 3'-end processing →	+0.080	+0.210	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,304 associations by consensus.

Negative regulation of epidermal growth factor-activated receptor activity by RNU6-542P expression — STAD

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