RNU6-542P

Across TCGA pan-cancer cohorts, RNU6-542P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-542P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-542P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-542P expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

UCS, PAAD, and CESC are the cancer types where RNU6-542P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.173	0.697	.001	108	view →
PAAD	DFS	Tertile	All	0.194	0.495	<.001	54	view →
CESC	OS	Tertile	II,III,IV	0.397	0.835	<.001	54	view →
LUSC	DFS	Tertile	II,III,IV	0.079	0.750	<.001	42	view →
LUAD	DFS	Tertile	All	0.920	0.622	.006	36	view →
OV	DFS	Tertile	IV	0.200	0.478	.007	18	view →
SKCM	OS	Tertile	III,IV	0.233	0.705	.034	9	view →
KIRP	OS	Tertile	III,IV	0.178	0.660	.044	9	view →
LIHC	DFS	Tertile	II,III,IV	0.080	0.414	.027	9	view →
KIRC	OS	Tertile	II,III,IV	0.274	0.544	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-542P–UCS (OS)

Open the UCS breakdown →