RNU6-540P

Across TCGA pan-cancer cohorts, RNU6-540P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-540P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-540P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-540P expression acts as an unfavorable survival marker, although some lineages such as BRCA and STAD show a favorable association.

CHOL, BRCA, and COAD are the cancer types where RNU6-540P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	72	view →
BRCA	OS	Tertile	All	0.983	0.952	<.001	70	view →
COAD	DFS	Tertile	III,IV	0.303	0.556	.008	51	view →
READ	DFS	Tertile	III,IV	0.307	0.779	<.001	42	view →
UCEC	OS	Tertile	IV	0.066	0.755	<.001	36	view →
CESC	DFS	Tertile	IV	0.163	0.543	.015	36	view →
SKCM	OS	Tertile	III,IV	0.691	0.863	.018	18	view →
LIHC	DFS	Tertile	All	0.376	0.557	.007	15	view →
BLCA	DFS	Tertile	IV	0.310	0.503	.017	9	view →
ACC	OS	Tertile	III,IV	0.208	0.650	.032	9	view →
PCPG	OS	Tertile	All	0.939	1.000	.034	9	view →
STAD	OS	Median	All	0.728	0.600	.014	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-540P–CHOL (DFS)

Open the CHOL breakdown →