RNU6-539P

Across TCGA patient cohorts, RNU6-539P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,471 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-539P-associated GO terms across cancer lineages are Telomere organization, Regulation of RNA splicing, and DNA modification. Each is linked with RNU6-539P in more than 17 cancer types. Because this analysis shows association rather than direction, both RNU6-539P-to-partner and partner-to-RNU6-539P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere organization grouped by RNU6-539P-low versus RNU6-539P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-539P→partner) and Y-score (partner→RNU6-539P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Telomere organization →	+0.046	+0.680	<.001	<.001	3	18
STAD	Regulation of RNA splicing →	+0.061	+0.668	<.001	<.001	3	18
STAD	DNA modification →	+0.042	+0.661	<.001	<.001	3	18
STAD	Methylation →	+0.044	+0.603	<.001	<.001	3	18
STAD	3'-UTR-mediated mRNA stabilization →	+0.048	+0.646	<.001	<.001	3	17
STAD	Peptidyl-lysine modification →	+0.051	+0.726	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,471 associations by consensus.

Telomere organization by RNU6-539P expression — ESCA

Explore this box plot interactively →