RNU6-524P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-524P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-524P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-524P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-524P expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

ACC, STAD, and BLCA are the cancer types where RNU6-524P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSTertileAll0.0100.667<.001135view →
STADDFSTertileAll0.5000.682<.001132view →
BLCAOSTertileIII,IV0.2270.694<.00178view →
LUSCOSTertileIV0.0010.673.01436view →
READOSTertileII,III,IV0.2870.816.00136view →
LUADOSQuartileII,III,IV0.4090.641.00118view →
SKCMDFSTertileIII,IV0.0430.597<.00118view →
OVOSTertileAll1.0000.683.03012view →
PRADOSTertileAll0.9380.996.03112view →
UCSDFSTertileAll1.0000.224.0496view →
KIRPOSTertileAll0.8570.956.0226view →
KIRCDFSTertileIV0.6650.433.0394view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration