RNU6-504P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-504P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-504P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-504P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-504P expression acts as an unfavorable survival marker, although some lineages such as OV and LIHC show a favorable association.

CHOL, OV, and UCEC are the cancer types where RNU6-504P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileII,III,IV0.0660.761<.001117view →
OVDFSTertileII,III,IV0.4520.362.01736view →
UCECDFSTertileAll0.7590.900.00236view →
MESODFSTertileII,III,IV0.1920.521.02427view →
LIHCDFSTertileIII,IV0.7610.160.03024view →
BLCAOSTertileAll0.2310.604.02318view →
STADOSQuartileAll0.7750.619.00916view →
THYMOSTertileII,III,IV0.3950.863.01412view →
TGCTDFSTertileAll0.6770.853.02512view →
PAADOSTertileAll0.2170.528.0269view →
COADDFSTertileIV0.0280.496<.0019view →
KIRPOSTertileAll0.8690.953.0346view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-504P–CHOL (OS)

Kaplan–Meier survival curve for RNU6-504P RNA-high vs -low samples in CHOL.

Open the CHOL breakdown →

Exploration