RNU6-504P

Across TCGA pan-cancer cohorts, RNU6-504P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-504P’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RNU6-504P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-504P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

ESCA, KICH, and THCA are the cancer types where RNU6-504P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-504P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+1.120	.013	3	view →
KICH	All	All	+0.139	.003	3	view →
THCA	Female	All	−0.157	.024	2	view →
STAD	All	All	+0.134	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-504P–ESCA

Open the ESCA breakdown →