RNU6-453P

Across TCGA pan-cancer cohorts, RNU6-453P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-453P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-453P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-453P expression acts as an unfavorable survival marker, although some lineages such as STAD and LGG show a favorable association.

BLCA, STAD, and READ are the cancer types where RNU6-453P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.158	0.466	.016	39	view →
STAD	OS	Tertile	IV	1.000	0.277	.023	36	view →
READ	OS	Tertile	III,IV	0.328	0.751	.003	36	view →
LIHC	OS	Tertile	All	0.144	0.688	.013	27	view →
LGG	OS	Tertile	All	0.791	0.472	.001	27	view →
THCA	DFS	Tertile	IV	0.409	0.721	.010	21	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
UCS	DFS	Tertile	All	1.000	0.213	.016	18	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
SARC	DFS	Tertile	All	0.360	0.617	.022	12	view →
PCPG	OS	Tertile	All	0.925	1.000	.017	9	view →
MESO	OS	Tertile	III,IV	0.328	0.586	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-453P–BLCA (OS)

Open the BLCA breakdown →