RNU6-438P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-438P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-438P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-438P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-438P expression acts as an unfavorable survival marker, although some lineages such as UCS and PRAD show a favorable association.

KIRC, KIRP, and ACC are the cancer types where RNU6-438P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.4790.872<.00196view →
KIRPDFSTertileAll0.2630.865<.00196view →
ACCOSTertileAll0.1260.638.00172view →
MESOOSTertileIV0.0360.602<.00172view →
LIHCDFSTertileAll0.3850.565.00251view →
BRCAOSQuartileAll0.9410.970.00528view →
LUADOSMedianAll0.6390.751.01320view →
HNSCOSMedianAll0.3140.428.00918view →
UCSOSQuartileII,III,IV0.7410.403.03014view →
THCAOSTertileAll0.9110.982.00612view →
PRADDFSTertileAll0.9740.919.00312view →
THYMOSMedianII,III,IV0.8880.983.03411view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration