RNA, U6 small nuclear 438, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-438P profile across patient tissues and cancer cell-line models. RNU6-438P expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RNU6-438P is differentially expressed in 10, with the highest sampling consensus in HNSC. Additionally, RNU6-438P RNA expression shows 11,274 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRP, HNSC, and THYM as cancer lineages where RNU6-438P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-438P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-438P survival associations across molecular data types. RNU6-438P RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-438P RNA expression–survival associations across cancer types. High RNU6-438P expression shows unfavorable associations in KIRP, KIRC, ACC, MESO, LIHC and BRCA. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for RNU6-438P RNA expression.
This table summarizes RNU6-438P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-438P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-438P shows higher tumor expression in HNSC, LUSC, LUAD, BRCA, COAD and PAAD. The HNSC box plot shows higher RNU6-438P RNA expression in tumor versus normal tissue (log2 FC = +1.646, t-test p < 0.001).
This table shows molecular features associated with RNU6-438P in patient tissues and cancer cell lines. In patient samples, RNU6-438P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
