RNU6-430P

Across TCGA pan-cancer cohorts, RNU6-430P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-430P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-430P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-430P expression acts as an unfavorable survival marker, although some lineages such as LAML and CESC show a favorable association.

CHOL, MESO, and ACC are the cancer types where RNU6-430P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.675	<.001	90	view →
MESO	OS	Tertile	III,IV	0.296	0.603	.005	66	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	63	view →
STAD	DFS	Median	All	0.599	0.803	.005	32	view →
ESCA	OS	Tertile	All	0.536	0.784	.002	30	view →
LAML	DFS	Median	All	0.542	0.207	.001	30	view →
THYM	OS	Tertile	III,IV	0.212	0.953	.009	27	view →
BLCA	DFS	Tertile	IV	0.261	0.507	.005	24	view →
KICH	DFS	Tertile	All	0.334	0.881	.021	21	view →
CESC	OS	Tertile	IV	0.744	0.248	.049	18	view →
SKCM	DFS	Tertile	All	0.084	0.214	.019	12	view →
PRAD	OS	Tertile	All	0.966	0.997	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU6-430P–CHOL (OS)

Open the CHOL breakdown →