RNA, U6 small nuclear 415, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-415P profile across patient tissues and cancer cell-line models. RNU6-415P expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in PAAD. Among the 18 cancer types available for tumor–normal comparison, RNU6-415P is differentially expressed in 14, with the highest sampling consensus in LUAD. Additionally, RNU6-415P RNA expression shows 16,799 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight PAAD, LUAD, and UVM as cancer lineages where RNU6-415P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-415P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-415P survival associations across molecular data types. RNU6-415P RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-415P RNA expression–survival associations across cancer types. High RNU6-415P expression shows unfavorable associations in KIRP, but favorable associations in PAAD, LAML, READ, BRCA and UVM. The PAAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify PAAD as the clearest survival context for RNU6-415P RNA expression.
This table summarizes RNU6-415P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-415P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-415P shows lower tumor expression in LUAD, COAD, THCA, LUSC, KIRP and HNSC. The LUAD box plot shows higher RNU6-415P RNA expression in normal versus tumor tissue (log2 FC = −1.684, t-test p < 0.001).
This table shows molecular features associated with RNU6-415P in patient tissues and cancer cell lines. In patient samples, RNU6-415P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
