RNU6-414P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-414P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-414P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-414P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-414P expression acts as an unfavorable survival marker, although some lineages such as STAD and LUSC show a favorable association.

TGCT, ACC, and PAAD are the cancer types where RNU6-414P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileIII,IV0.0031.000<.00190view →
ACCOSTertileAll0.2680.802.01036view →
PAADDFSTertileII,III,IV0.2360.450.01336view →
GBMDFSTertileAll0.0610.288<.00127view →
ESCADFSTertileIV0.1430.704.02427view →
STADOSQuartileAll0.6840.477.00923view →
THCAOSTertileII,III,IV0.9130.988.01121view →
BLCAOSTertileIV0.1850.599.00418view →
THYMDFSTertileAll0.0750.885<.00118view →
LUSCDFSQuartileII,III,IV0.9250.435.00913view →
BRCAOSTertileII,III,IV0.7500.528.02312view →
LUADOSTertileAll0.6750.323.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration