Across TCGA pan-cancer cohorts, RNU6-414P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-414P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-414P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-414P is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

BRCA, KICH, and PRAD are the cancer types where RNU6-414P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-414P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.294	.016	4	view →
KICH	All	All	−0.274	.013	3	view →
PRAD	All	All	+0.141	.041	2	view →
THCA	All	All	−0.111	.007	2	view →
LUSC	All	All	+0.126	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-414P RNA expression & survival · all RNU6-414P data types