RNU6-407P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-407P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-407P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-407P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-407P expression acts as an unfavorable survival marker, although some lineages such as BRCA and BLCA show a favorable association.

BRCA, KIRP, and LIHC are the cancer types where RNU6-407P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSQuartileAll0.9290.877.00649view →
KIRPOSTertileII,III,IV0.1750.782.00236view →
LIHCDFSTertileAll0.3910.579.01133view →
KIRCOSTertileAll0.5040.702.00426view →
BLCAOSMedianAll0.5840.341.00420view →
GBMOSTertileAll0.3070.183.00820view →
LUADOSTertileAll0.6170.777.00520view →
SARCOSTertileAll0.2820.677<.00119view →
LUSCOSQuartileAll0.3250.486.00914view →
COADOSQuartileIV0.7440.450.01114view →
THCADFSTertileIII,IV0.7580.907.01510view →
UVMOSTertileIII,IV0.3080.717.0199view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration