RNU6-407P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-407P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-407P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU6-407P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-407P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, KIRC, and COAD are the cancer types where RNU6-407P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-407P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllIII,IV+0.402.0018view →
KIRCAllAll+0.208.0085view →
COADAllAll+0.431.0014view →
LIHCAllAll+0.135.0084view →
CHOLAllAll+0.794.0032view →
BRCAAllIII,IV−0.412.0412view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

Exploration