RNU6-406P

Across TCGA pan-cancer cohorts, RNU6-406P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-406P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-406P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-406P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

STAD, ESCA, and MESO are the cancer types where RNU6-406P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.354	0.570	.002	72	view →
ESCA	OS	Tertile	All	0.875	0.632	.007	54	view →
MESO	OS	Tertile	III,IV	0.036	0.563	<.001	54	view →
PRAD	DFS	Tertile	All	0.677	0.937	<.001	30	view →
LUAD	DFS	Tertile	II,III,IV	0.269	0.586	.003	24	view →
KIRC	DFS	Tertile	All	0.141	0.631	<.001	18	view →
KIRP	OS	Tertile	II,III,IV	0.178	0.743	.013	18	view →
PCPG	DFS	Tertile	All	0.229	0.821	.031	18	view →
LGG	DFS	Tertile	All	0.294	0.759	.005	18	view →
GBM	DFS	Tertile	All	0.087	0.291	.022	9	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	9	view →
LIHC	DFS	Tertile	III,IV	0.066	0.426	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-406P–STAD (DFS)

Open the STAD breakdown →