RNU6-405P

Across TCGA patient cohorts, RNU6-405P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,365 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-405P-associated GO terms across cancer lineages are Negative regulation of DNA metabolic process, Regulation of nucleotide metabolic process, and Electron transport chain. Each is linked with RNU6-405P in more than 3 cancer types. Because this analysis shows association rather than direction, both RNU6-405P-to-partner and partner-to-RNU6-405P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA metabolic process grouped by RNU6-405P-low versus RNU6-405P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-405P→partner) and Y-score (partner→RNU6-405P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA metabolic process →	+0.132	+0.104	<.001	<.001	3	4
STAD	Regulation of nucleotide metabolic process →	+0.102	+0.110	<.001	<.001	3	4
STAD	Electron transport chain →	+0.169	+0.107	<.001	<.001	3	4
STAD	Dicarboxylic acid metabolic process →	+0.113	+0.098	<.001	<.001	3	4
STAD	Vesicle localization →	+0.133	+0.103	<.001	<.001	3	3
STAD	Spindle localization →	+0.150	+0.106	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,365 associations by consensus.

Negative regulation of DNA metabolic process by RNU6-405P expression — STAD

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