RNU6-405P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-405P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-405P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-405P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-405P expression acts as an unfavorable survival marker.

BLCA, HNSC, and KIRP are the cancer types where RNU6-405P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll0.1350.711<.001198view →
HNSCOSTertileAll0.1410.663<.001180view →
KIRPOSTertileAll0.1800.904<.00145view →
BRCADFSTertileAll0.7810.951<.00142view →
STADOSTertileIV0.0740.496.00236view →
SKCMDFSTertileIII,IV0.0400.613<.00136view →
SARCDFSTertileAll0.0690.632<.00127view →
LUADOSTertileAll0.3980.838<.00118view →
PRADOSTertileAll0.8110.990<.00118view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-405P–BLCA (OS)

Kaplan–Meier survival curve for RNU6-405P RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration