RNU6-396P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-396P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-396P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-396P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-396P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LGG show a favorable association.

STAD, READ, and CHOL are the cancer types where RNU6-396P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSQuartileAll0.5160.776<.00163view →
READDFSTertileIII,IV0.2550.757.00845view →
CHOLOSTertileAll0.0190.800<.00136view →
ACCDFSTertileAll0.1170.601.00327view →
TGCTDFSTertileAll0.0690.689<.00118view →
ESCAOSMedianIII,IV0.6650.464.0329view →
GBMOSTertileAll0.1260.421.0209view →
COADOSTertileIV0.1400.657.0359view →
LGGOSTertileAll0.9400.797.0326view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration