RNU6-388P

Across TCGA pan-cancer cohorts, RNU6-388P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-388P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-388P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-388P expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

UCS, HNSC, and BLCA are the cancer types where RNU6-388P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	III,IV	0.702	0.265	.004	82	view →
HNSC	DFS	Tertile	II,III,IV	0.571	0.242	<.001	60	view →
BLCA	OS	Tertile	All	0.577	0.306	<.001	54	view →
BRCA	DFS	Tertile	III,IV	0.514	0.383	.001	46	view →
CESC	OS	Median	III,IV	0.216	0.556	.016	28	view →
LGG	DFS	Median	All	0.797	0.866	.005	24	view →
ACC	DFS	Tertile	II,III,IV	0.446	0.757	.003	23	view →
THYM	DFS	Median	All	1.000	0.802	.001	21	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	21	view →
DLBC	DFS	Tertile	IV	1.000	0.136	.006	21	view →
LIHC	DFS	Quartile	II,III,IV	0.198	0.378	.018	18	view →
KIRP	DFS	Quartile	III,IV	0.122	0.761	.009	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU6-388P–UCS (OS)

Open the UCS breakdown →