RNU6-387P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-387P RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNU6-387P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-387P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-387P expression acts as an unfavorable survival marker, although some lineages such as THYM and LUAD show a favorable association.

UVM, LIHC, and UCEC are the cancer types where RNU6-387P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMDFSQuartileAll0.4470.833.00157view →
LIHCOSQuartileAll0.6710.817.00154view →
UCECDFSQuartileII,III,IV0.4850.723.01738view →
ACCDFSMedianIV0.0660.495.00126view →
KIRPDFSMedianIII,IV0.5660.851.00626view →
LGGDFSTertileAll0.2420.428.00124view →
COADDFSQuartileII,III,IV0.3470.624.00721view →
PCPGDFSMedianAll0.6180.907.00513view →
CHOLOSMedianIII,IV0.2861.000.00812view →
LUSCDFSTertileIII,IV0.2820.802.02411view →
THYMDFSMedianII,III,IV0.9470.533.0069view →
LUADOSQuartileII,III,IV0.4040.103.0199view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration