RNU6-387P

associated omics data
RNA, U6 small nuclear 387, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-387P profile across patient tissues and cancer cell-line models. RNU6-387P expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, RNU6-387P is differentially expressed in 10, with the highest sampling consensus in STAD. Additionally, RNU6-387P RNA expression shows 16,081 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight UVM, STAD, and DLBC as cancer lineages where RNU6-387P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-387P survival associations across molecular data types. RNU6-387P RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-387P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier24UVM (57)view →
This table ranks reproducible RNU6-387P RNA expression–survival associations across cancer types. High RNU6-387P expression shows unfavorable associations in UVM, LIHC, UCEC, ACC, KIRP and LGG. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UVM as the clearest survival context for RNU6-387P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMDFSQuartileAll0.4470.833.00157view →
LIHCOSQuartileAll0.6710.817.00154view →
UCECDFSQuartileII,III,IV0.4850.723.01738view →
ACCDFSMedianIV0.0660.495.00126view →
KIRPDFSMedianIII,IV0.5660.851.00626view →
LGGDFSTertileAll0.2420.428.00124view →
Pink = unfavorable, green = favorable. all 24 lineages →

RNU6-387P-UVM (DFS)

Kaplan–Meier survival curve for RNU6-387P RNA expression in UVM: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-387P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in STAD for RNA.
RNU6-387P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot10STAD (4)view →
This table ranks reproducible tumor–normal expression differences for RNU6-387P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-387P shows higher tumor expression in STAD, READ, CHOL, ESCA, COAD and LUAD. The STAD box plot shows higher RNU6-387P RNA expression in tumor versus normal tissue (log2 FC = +0.936, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
STADAllAll+0.936<.0014view →
READFemaleAll+1.283<.0012view →
CHOLAllAll+1.075.0022view →
ESCAAllAll+0.648.0242view →
COADMaleAll+0.590.0232view →
LUADAllAll+0.492.0052view →
Green = repressed in tumor. all 10 lineages →

RNU6-387P-STAD

Tumor-vs-normal expression box plot for RNU6-387P in STAD.

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Cross-omics associations

This table shows molecular features associated with RNU6-387P in patient tissues and cancer cell lines. In patient samples, RNU6-387P shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA16,081DLBC (6708)view →
Protein (mass-spec)7,375GBM (3916)view →