RNU6-377P

Across TCGA pan-cancer cohorts, RNU6-377P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-377P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-377P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-377P expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

MESO, BLCA, and HNSC are the cancer types where RNU6-377P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	II,III,IV	0.248	0.437	.003	63	view →
BLCA	OS	Median	III,IV	0.457	0.285	.001	39	view →
HNSC	OS	Tertile	II,III,IV	0.736	0.624	.022	24	view →
SKCM	OS	Median	III,IV	0.795	0.624	.014	17	view →
BRCA	DFS	Tertile	III,IV	0.607	0.422	.011	16	view →
KIRP	DFS	Median	III,IV	0.748	0.460	.010	15	view →
TGCT	DFS	Median	All	0.484	0.782	.018	12	view →
THYM	OS	Tertile	II,III,IV	0.852	0.964	.025	12	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	11	view →
UVM	OS	Tertile	III,IV	0.350	0.757	.029	6	view →
KIRC	DFS	Quartile	II,III,IV	0.566	0.791	.012	6	view →
COAD	DFS	Quartile	All	0.348	0.643	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-377P–MESO (OS)

Open the MESO breakdown →